OMICS Intensive Module

DNA analysis. Image courtesy of Berkeley Lab, Flickr

DNA analysis. Image courtesy of Berkeley Lab, Flickr

Genomics, proteomics, transcriptomics and metabolomics. These are some of the rising stars of biology studies, which are informally referred to as OMICS.

This summer Skoltech offers students and researchers a unique opportunity to get acquainted with and gain hands-on experience in cutting edge “OMICS Data Analysis and Medical Applications”.

The university’s Center for Data-Intensive Biomedicine and Biotechnology (CDIB) organizes in collaboration with Rusnano an intensive one-week educational module (July 20-26), jam-packed with presentations by some of the world’s leading scientists in the field. The program was developed in collaboration with top research institutes, including Institut Curie (France), University of Oxford (UK), Harvard Medical School (USA), and the Max Planck Institute for Computational Biology (Shanghai, China).

The program will provide an introduction to OMICS to the 20 competitively selected participants – Skoltech Ph.D. students, researchers from labs across Russia and employees of big companies. Instructors will review novel research methods, present practical applications in clinical diagnostics, therapy, pharmacy, and experimental biomedicine, and help attendees gain critical hands-on skills in computational biomedicine.

Program

Monday, July 20th

09:00               Registration

10:00               Introduction to the course

Tatiana Nikolenko, Andrey Zinovyev, Alexander Kanapin

11:00               Lecture: Omics data in precision oncology: past, present, and future

Emmanuel Barillot

13:00               Lunch

14:00               Lecture: Types of omics data and current omics technology overview

Alexander Kanapin

16:00               Omics data in virology

Manja Marz

18:00               Discussion

19:30               Welcome Party

Tuesday, July 21st

09:00               Lecture: Modern methods for visualization and exploratory analysis of omics data

Andrei Zinovyev

11:00               Lecture: High-throughput sequencing of the genome, epigenome and transcriptome for studying cancer

Valentina Boeva

13:00               Lunch

14:00               Lecture: Single cell omics data analysis and projects

Peter Kharchenko

16:00               Lecture: Modern computational infrastructure for omics data analysis

Lennart C. Karssen

18:00               Break

19:00               Practical session: High-throughput sequencing computational tools

Valentina Boeva + assistants

20:30               Dinner

Wednesday, July 22nd

09:00               Lecture: Machine learning for precision medicine and analysis of omics data (Part 1)

Felix Agakov

11:00               Lecture: Mobile genetic elements: postgenomic view

Alexander Kanapin

13:00               Lunch

14:00               Lecture: Cancer genome and approaches for understanding it

Tatiana Popova

16:00               Lecture: European genomics programs: objectives and challenges

Alexander Kanapin

18:00               Break

19:00               Practical session: Analyzing cancer genome

Tatiana Popova + assistants

20:30               Dinner

Thursday, July 23rd

09:00               Lecture: Machine learning for precision medicine and analysis of omics data (Part 2)

Felix Agakov

11:00               Lecture: Gut metagenomics and its application in medicine

Dmitry Ravcheev

13:00               Lunch

14:00               Lecture: Genomic instability and cancer prognosis, treatment and predisposition

Tatiana Popova

16:00               Lecture: Constructing, maintaining and using databases of molecular networks in medical applications

Maria Kondratova

18:00               Break

19:00               Practical session: Tools for dimension reduction and data visualization

Andrei Zinovyev + assistants

20:30               Dinner

Friday, July 24th

09:00               Lecture: How to decipher the biological and medical impact of somatic events in cancer?

Ekaterina Kotelnikova

11:00               Lecture: Mathematical modeling of biological processes using omics data

Andrei Zinovyev

13:00               Lunch

14:00               Lecture: Perspectives of precision medicine in Russia and worldwide

Evgeny Imyanitov

16:00               Lecture: Omics data for studying brain in health and disease

Philipp Khaitovich

18:00               Break

19:00               Practical session: Use of network-based methods for analysis of omics data

Maria Kondratova+assitants

20:30               Dinner

Saturday, July 25th

09:00               Lecture: The regulatory sequence level of protein-nucleic acids interaction: what we can and can’t do with sequence motif analysis of high-throughput omics data

Ivan Kulakovsky

11:00               Lecture: Discovery and analysis of eukaryotic enhancers using alternative genomic approaches

Dmitri Papatsenko

13:00               Lunch

14:00               Lecture: Algorithms of biological network analysis together with omics data

Mikhail Pyatnitskiy

16:00               Group discussion with lecturers: Q&A

18:00               Break

19:00               Remote lecture: Omics data for studying aging

Vadim Gladyshev

20:30               Dinner

Sunday, July 26th

09:00               Lecture: Evolutionary studies of human brain

Philipp Khaitovich

11:00               Lecture: Sniderome and similar projects and the future of personalized omics medicine

Andrei Zinovyev

13:00               Lunch

14:00               Summary and final discussion

18:00               Departure

 

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