Skoltech Colloquium: “Reading Chemical “Fine Print”: The Key to Exploiting Nature’s Compositional Complexity”

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Speaker: Dr. Alan G. Marshall

Ion Cyclotron Resonance Program of National High Magnetic Field Lab and Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL, USA

Abstract

Most mass analysis relies on “nominal” mass accuracy (i.e., to within 1 Da).  However, more and more applications are based on much more accurate mass measurement.  Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) offers 10-1000 times higher mass resolving power than other mass analyzers.

High mass resolving power (m/Dm50% > 1,000,000) offers two major advantages: (a) it becomes possible to separate complex mixtures without prior chromatographic or gel separation; and (b) elemental composition may be determined from accurate (to within less than 100 ppb) mass measurement alone for unknown molecules up to ~1,000 Da.  Examples from environmental, petrochemical, analytical, and biological (e.g., proteomics & lipidomics) problems will be presented.

If you like to participate and for further information or questions, please Liliya Abaimova
We look forward to seeing you.

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