Proteins change as the immune system alters and so can be used as a measure of how it is functioning. Blood was taken from the cosmonauts 30 days before they travelled to the ISS and then on their immediate return to Earth. They were also tested seven days after touchdown. Individual proteins were then counted using a mass spectrometer.
”When we examined the cosmonauts after their being in space for half a year, their immune system was weakened,” said Dr Irina Larina, the first author of the paper, a member of Laboratory of Ion and Molecular Physics of Moscow Institute of Physics and Technology.
“They were not protected from the simplest viruses. We need new measures of disorder prevention during a long flight.
“We must understand the mechanism that causes disorders. If we find the pathways that are affected by the weightlessness, we will be able to find the target for the remedy and we’ll be able to offer new pharmaceutical products that will prevent these negative processes.”
The research was published in the journal Nature Scientific Reports.