Skoltech is an international graduate research-focused university that was founded by the group of world-renowned scientists in 2011. Skoltech's curriculum focuses on technology and innovation, offering Master's programs in 11 technological disciplines. Students receive rigorous theoretical and practical training, design their own research projects, participate in internships and gain entrepreneurial skills in English. The faculty is comprised of current researchers with international accreditation and achievements.

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Seminar by Dr. Alexej Abyzov

Detecting Genomic Variations in Human Cells and Determining Their Impact

Guest Speaker: Dr. Alexej Abyzov

When: 13:00 – 14:30, Sept. 19

Where: Pekin Auditorium, Skolkovo School of Management

Dr. Alexej Abyzov visits Skoltech to present on analyzing genome structural variations using sequence data, outlining their advantages and limitations. This should demonstrate how identifying a comprehensive set of personal variants can lead to the generation of a biological hypothesis about cell processes, allow for understanding of the stability of iPSC genomes, and enable evaluation of the extent of somatic variants in individual cells (lecture in English).

Attendance is limited to 20. If you would like to participate, please e-mail by September 18. We will be unable to accept more applicants later than 17:00 on September 18, so please be sure to inform her as early as possible.

Seminar Description:

Genome variations, particularly structural genome variations, is a complex not completely understood phenomenon. In humans, genome variations have been linked to cancer as well as to inherited and Mendelian diseases. The wealth of recent genomic sequencing data enables the studying of genome variations on an unprecedented scale (from the analysis of large populations to understanding somatic variations within a single individual) and with unprecedented accuracy (often with single base pair resolution).

In his seminar, Dr. Alexej Abyzov will first describe several methodologies that he has developed to analyze genome structural variations using sequence data, outlining their advantages and limitations. He will then demonstrate how identifying a comprehensive set of personal variants is crucial for the discovery of de novo variants, serves as a basis for unbiased functional analyses, leads to the generation of a biological hypothesis about cell processes, allows for understanding of the stability of iPSC genomes, and enables evaluation of the extent of somatic variants in individual cells.

Guest Spearker:

Dr. Alexej Abyzov is a computational biologist with focus research areas in genomics and proteomics. His goal is to contribute to the fundamental understanding of how variations in genome(s) lead to phenotypic variations, cause diseases and/or promote cancer. As part of this goal, he wants to apply new knowledge to find ways to prevent and treat various diseases and cancer.

Dr. Alexej Abyzov received his BS and MS degrees in physics from Moscow Institute of Physics and Technology (MIPT) in 2000 and 2002, respectively, and a Ph.D. in Biology from Northeastern University in Boston in 2008. Since, 2008 he has been working in the laboratory of Mark Gerstein in Yale University. As of the end of last year he holds a position of Associated Research Scientist. He has authored over thirty peer-reviewed publications, including such prestigious journals as Science and Nature, and the reviewer in a number of scientific journals.

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