Skoltech is an international graduate research-focused university that was founded by the group of world-renowned scientists in 2011. Skoltech's curriculum focuses on technology and innovation, offering Master's programs in 11 technological disciplines. Students receive rigorous theoretical and practical training, design their own research projects, participate in internships and gain entrepreneurial skills in English. The faculty is comprised of current researchers with international accreditation and achievements.

Skoltech Colloquium on April 10

We are pleased to invite you to the Skoltech Colloquium!

image001-3Guest Speaker: Dr. Alexandre Shvartsburg was born in Moscow in 1971. He earned his M.S (Chemistry) from the Univ. of Nevada, Reno in 1995 and Ph.D (Chemistry) from Northwestern in 1999. He was a NSERC Postdoctoral Fellow at York Univ. (Toronto) and Staff Fellow of the US Food and Drug Administration (Jefferson, Arkansas). He moved to the Pacific Northwest National Laboratory (Richland, Washington) in 2003 and is presently a Senior Scientist with the Biological Sciences Division.

The main focus of Dr. Shvartsburg’s research is mass spectrometry (MS) and ion mobility spectrometry (IMS) coupled to MS, and applications of IMS/MS to the structural characterization of nanomaterials and biological macromolecules and rapid and selective isomer separations. Over the last few years, his interests have shifted to the novel IMS approach of field asymmetric waveform IMS (FAIMS) based on the difference between ion mobilities in strong and weak electric fields, and its bioanalytical applications. Advancing that technology has led him to conceptualize and explore novel nonlinear IMS methods that leverage the dependence of mobility on the field in new ways.

When: April 10; 4:00pm.

Where: Institute of Gene Biology RAS, Vavilova street 34/5, Conference room, 1st floor.

What: High-Resolution Nonlinear Ion Mobility Separations with Mass Spectrometry and Selected Bioanalytical Applications.

Abstract: Ion mobility spectrometry (IMS) is a method for analytical separation and characterization of ions, employing the properties of their transport through gases driven by electric field. The two branches of IMS are conventional or linear, based on the absolute ion mobility, and emerging differential or nonlinear, leveraging the dependence of mobility on the field strength. A major attraction of differential or field asymmetric waveform IMS (FAIMS) is high orthogonality to mass spectrometry (MS), far exceeding that of conventional IMS where the mobility is tightly correlated to the ion size and thus to mass. New gas compositions, elevated fields, and longer separations have raised the FAIMS resolving power from ~10 to ~100 – 500. This resolving power and orthogonality to MS have allowed FAIMS to distinguish many species, in particular structural isomers, co-eluting in conventional IMS. Examples include isomeric lipids with differing fatty acid attachment sites, peptides with sequence inversions or variant localization of post-translational modifications, and even isotopomers. Hydrogen-rich gas buffers have recently permitted separating protein conformers with extreme resolution, apparently isolating individual geometries for the first time by any solution or gas-phase technique. These unique capabilities open the door to previously unthinkable proteomic and metabolomic applications

Transfers:

Shuttle bus Hypercube → Institute of Gene Biology RAS at 3:10 pm

Shuttle bus MSM (Karacorum) → Institute of Gene Biology RAS at 3:20 pm

How to get to Institute of Gene Biology RAS:

Address: Vavilova street 34/5 (ул. Вавилова 34/5)

Map: http://www.genebiology.ru/institute/way.shtml

Join us on Facebook: https://www.facebook.com/pages/Skoltech-Colloquium/667982569920574

Past schedule and video: https://www.skoltech.ru/en/colloquium/past-schedule

If you like to participate and for further information or questions, please Liliya Abaimova
We look forward to seeing you.

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