Analytical instrumentation, calibration transfer, chemometrics
Calibration transfer between any two analytical instruments addressing the same analytical task
Calibration process for an analytical instrument may be long and tedious and may require the measurements with numerous standard samples which can be pretty expensive. Calibration model obtained for one instrument normally cannot be used directly with another, this leads to necessity of calibration for each particular instrument in use resulting in high costs for the maintenance.
We suggest a procedure to avoid the calibration of the second instrument with the whole set of standard samples and measure only small subset of standards instead. After that based on the results of measurements with two instruments in the same small number of standard samples a mathematical transformation is performed to adjust the signal of the second instrument into the format of the first one. This allows for using the whole calibration model of the first instrument with the data from the second instrument. Unlike other calibration transfer protocols suggested so far the present one can deal with the signals from different analytical instruments having different nature of analytical signal, different number of variables in the signal. For example calibration model from X-ray fluorescence spectrometer can be transferred to UV-Vis spectrometer.
A software demo package that showcases advantages of the patent-pending algorithm is available on request.
If you are interested in this technology please contact the KTO staff to discuss licensing opprotunities or R&D collaboration